Isocitrate dehydrogenase 2 inhibitor enasidenib synergizes daunorubicin cytotoxicity by targeting aldo-keto reductase 1C3 and ATP-binding cassette transporters.

Morell A, Budagaga Y, Vagiannis D, Zhang Y, Laštovičková L, Novotná E, Haddad A, Haddad M, Portillo R, Hofman J, Wsól V

Arch. Toxicol. (2022) doi: 10.1007/s00204-022-03359-2


Bruton's Tyrosine Kinase Inhibitors Ibrutinib and Acalabrutinib Counteract Anthracycline Resistance in Cancer Cells Expressing AKR1C3.

Morell A, Čermáková L, Novotná E, Laštovičková L, Haddad M, Haddad A, Portillo R, Wsól V.

Cancers (2020) 12, 3731.


Selective inhibition of aldo-keto reductase 1C3: a novel mechanism involved in midostaurin and daunorubicin synergism.

Morell A, Novotná E, Milan J, Danielisová P, Büküm N, Wsól V.

Arch. Toxicol. (2021) 95, 67-78.


Mucin 1 deficiency mediates corticosteroid insensitivity in asthma.

Milara J*, Morell A*, de Diego A, Artigues E, Morcillo E, Cortijo J.

Allergy (2019) 74, 111-121.


MUC4 impairs the anti-inflammatory effects of corticosteroids in patients with chronic rhinosinusitis with nasal polyps.

Milara J*, Morell A*, Ballester B, Armengot M, Morcillo E, Cortijo J.

J. Allergy Clin. Immunol. (2017) 139, 855-862.



Anselm Morell

I am a newcomer to plant research, after half a life working with steroids from a biomedical perspective. Hopefully I will be able to contribute with my experience in secondary metabolism and solve some pending issues in brassinosteroid synthesis.


- 2022 to present / CDEIGENT Researcher / IBMCP, Valencia, Spain.

- 2018 to 2022 / Postdoc at the Wsol Lab / Charles Univ, Prague, Czech Rep.

- 2014 to 2017 / PhD candidate at the Morcillo and Cortijo Lab / Universitat de València, Spain.

- 2013 to 2014 / MSc in Biomedical Biotechnology / UPV, Valencia, Spain

- 2007 to 2012 / Biology Degree / Universitat Pompeu Fabra, Barcelona, Spain

Hormone signaling and plasticity

Selected References

Contact details

anmog15@ibmcp.upv.es

Tel: +34 963 878 607

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MORELL